Estudo do Efeito da Concentração de  Gelatina na Morfologia e no Grau de  Intumescimento do Hidrogel

Jéssica  A. R. Ambrosio; Bruna C. dos S. Pinto; Vitor L. M. Marmo; Andreza R. Simioni

doi:10.19142/rpq.v17i31.631

Jéssica A. R. Ambrosio Laboratório de Síntese Orgânica, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos.
Bruna C. dos S. Pinto Laboratório de Síntese Orgânica, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos.
Vitor L. M. Marmo Laboratório de Síntese Orgânica, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos.
Andreza R. Simioni Laboratório de Síntese Orgânica, Instituto de Pesquisa e Desenvolvimento, Universidade do Vale do Paraíba, São José dos Campos.

DOI: https://doi.org/10.19142/rpq.v17i31.631

Palavras-chave: Hidrogel, Terapia fotodinâmica, Cloro alumínio ftalocianina

Resumo

Os sistemas hidrogel vem ganhando cada vez mais espaço em aplicações conjuntas com a engenharia biomédica. A Terapia fotodinâmica (TFD) é uma modalidade de tratamento que se baseia na combinação de um fotossensibilizador (FS), luz e o oxigênio molecular levando a formação de espécies reativas (ROS), como o oxigênio singleto, responsável pela morte celular do alvo. O objetivo do trabalho foi avaliar a influência da concentração de gelatina e da reticulação em três grupos de hidrogel. Os resultados foram avaliados por microscopia eletrônica de varredura (MEV) e quanto a capacidade de intumescimento (% GI).

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