A Bioeletricidade Pode Revolucionar a Medicina
Resumo
A Bioeletricidade Pode Revolucionar a Medicina
Referências
1. Harris, M. P. Bioelectric Signaling as a Unique Regulator of
Development and Regeneration. Development 2021, 148 (10).
https://doi.org/10.1242/DEV.180794.
2. Gascoyne, P.; Pethig, R.; Satayavivad, J.; Becker, F. F.; Ruchirawat,
M. Dielectrophoretic Detection of Changes in Erythrocyte
Membranes Following Malarial Infection. Biochim. Biophys.
Acta 1997, 1323 (2), 240–252. https://doi.org/10.1016/S0005-
2736(96)00191-5.
3. Heileman, K.; Daoud, J.; Tabrizian, M. Dielectric Spectroscopy
as a Viable Biosensing Tool for Cell and Tissue Characterization
and Analysis. Biosens. Bioelectron. 2013, 49, 348–359. https://doi.
org/10.1016/J.BIOS.2013.04.017.
4. Yang, J.; Huang, Y.; Wang, X.; Wang, X. B.; Becker, F. F.;
Gascoyne, P. R. C. Dielectric Properties of Human Leukocyte
Subpopulations Determined by Electrorotation as a Cell Separation
Criterion. Biophys. J. 1999, 76 (6), 3307. https://doi.org/10.1016/
S0006-3495(99)77483-7.
5. Zimmermann, D.; Zhou, A.; Kiesel, M.; Feldbauer, K.; Terpitz, U.;
Haase, W.; Schneider-Hohendorf, T.; Bamberg, E.; Sukhorukov,
V. L. Effects on Capacitance by Overexpression of Membrane
Proteins. Biochem. Biophys. Res. Commun. 2008, 369 (4),
1022–1026. https://doi.org/10.1016/J.BBRC.2008.02.153.
6. Theillet, F. X.; Binolfi, A.; Frembgen-Kesner, T.; Hingorani, K.;
Sarkar, M.; Kyne, C.; Li, C.; Crowley, P. B.; Gierasch, L.; Pielak,
G. J.; Elcock, A. H.; Gershenson, A.; Selenko, P. Physicochemical
Properties of Cells and Their Effectson Intrinsically Disordered
Proteins (IDPs). Chem. Rev. 2014, 114 (13), 6661. https://doi.
org/10.1021/CR400695P.
7. Galvani, A.; Aldini, G. De Viribus Electricitatis in Motu Musculari,
1st ed.; Apud Societatem Typographicam: Bologna, 1792; Vol. 1.
8. McCaig, C. D.; Rajnicek, A. M.; Song, B.; Zhao, M. Controlling
Cell Behavior Electrically: Current Views and Future Potential.
Physiol. Rev. 2005, 85 (3), 943–978. https://doi.org/10.1152/
PHYSREV.00020.2004.
9. Langman, L.; Burr, H. S. Electrometric Studies in Women With
Malignancy of Cervix Uteri. Science (80-. ). 1947, 105 (2721),
209–210. https://doi.org/10.1126/SCIENCE.105.2721.209.B.
10. Nuccitelli, R.; Nuccitelli, P.; Li, C.; Narsing, S.; Pariser, D. M.; Lui,
K. The Electric Field near Human Skin Wounds Declines with Age
and Provides a Noninvasive Indicator of Wound Healing. Wound
Repair Regen. 2011, 19 (5), 645–655. https://doi.org/10.1111/
J.1524-475X.2011.00723.X
11. Phillips, M. B.; Nigam, A.; Johnson, J. W. Interplay between Gating
and Block of Ligand-Gated Ion Channels. Brain Sci. 2020, 10 (12),
1–22. https://doi.org/10.3390/BRAINSCI10120928.
12. Luo, R.; Dai, J.; Zhang, J.; Li, Z. Accelerated Skin Wound Healing
by Electrical Stimulation. Adv. Healthc. Mater. 2021, 10 (16).
https://doi.org/10.1002/ADHM.202100557.
13. Levin, M. Bioelectric Signaling: Reprogrammable Circuits
Underlying Embryogenesis, Regeneration, and Cancer. Cell 2021,
184 (8), 1971–1989. https://doi.org/10.1016/J.CELL.2021.02.034.
14. Fraser, S. P.; Ozerlat-Gunduz, I.; Brackenbury, W. J.; Fitzgerald,
E. M.; Campbell, T. M.; Coombes, R. C.; Djamgoz, M. B. A.
Regulation of Voltage-Gated Sodium Channel Expression in
Cancer: Hormones, Growth Factors and Auto-Regulation. Philos.
Trans. R. Soc. Lond. B. Biol. Sci. 2014, 369 (1638). https://doi.
org/10.1098/RSTB.2013.0105.
15. Yildirim, S.; Altun, S.; Gumushan, H.; Patel, A.; Djamgoz, M. B. A.
Voltage-Gated Sodium Channel Activity Promotes Prostate Cancer
Metastasis in Vivo. Cancer Lett. 2012, 323 (1), 58–61. https://doi.
org/10.1016/J.CANLET.2012.03.036.
16. Djamgoz, M. B. A. Treatment of Cancer/Inhibition of Metastasis.
US20180346431A1, June 7, 2018.
17. Paré, J.-F.; Martyniuk, C. J.; Levin, M. Bioelectric Regulation
of Innate Immune System Function in Regenerating and Intact
Xenopus Laevis. npj Regen. Med. 2017 21 2017, 2 (1), 1–15.
https://doi.org/10.1038/s41536-017-0019-y.
Development and Regeneration. Development 2021, 148 (10).
https://doi.org/10.1242/DEV.180794.
2. Gascoyne, P.; Pethig, R.; Satayavivad, J.; Becker, F. F.; Ruchirawat,
M. Dielectrophoretic Detection of Changes in Erythrocyte
Membranes Following Malarial Infection. Biochim. Biophys.
Acta 1997, 1323 (2), 240–252. https://doi.org/10.1016/S0005-
2736(96)00191-5.
3. Heileman, K.; Daoud, J.; Tabrizian, M. Dielectric Spectroscopy
as a Viable Biosensing Tool for Cell and Tissue Characterization
and Analysis. Biosens. Bioelectron. 2013, 49, 348–359. https://doi.
org/10.1016/J.BIOS.2013.04.017.
4. Yang, J.; Huang, Y.; Wang, X.; Wang, X. B.; Becker, F. F.;
Gascoyne, P. R. C. Dielectric Properties of Human Leukocyte
Subpopulations Determined by Electrorotation as a Cell Separation
Criterion. Biophys. J. 1999, 76 (6), 3307. https://doi.org/10.1016/
S0006-3495(99)77483-7.
5. Zimmermann, D.; Zhou, A.; Kiesel, M.; Feldbauer, K.; Terpitz, U.;
Haase, W.; Schneider-Hohendorf, T.; Bamberg, E.; Sukhorukov,
V. L. Effects on Capacitance by Overexpression of Membrane
Proteins. Biochem. Biophys. Res. Commun. 2008, 369 (4),
1022–1026. https://doi.org/10.1016/J.BBRC.2008.02.153.
6. Theillet, F. X.; Binolfi, A.; Frembgen-Kesner, T.; Hingorani, K.;
Sarkar, M.; Kyne, C.; Li, C.; Crowley, P. B.; Gierasch, L.; Pielak,
G. J.; Elcock, A. H.; Gershenson, A.; Selenko, P. Physicochemical
Properties of Cells and Their Effectson Intrinsically Disordered
Proteins (IDPs). Chem. Rev. 2014, 114 (13), 6661. https://doi.
org/10.1021/CR400695P.
7. Galvani, A.; Aldini, G. De Viribus Electricitatis in Motu Musculari,
1st ed.; Apud Societatem Typographicam: Bologna, 1792; Vol. 1.
8. McCaig, C. D.; Rajnicek, A. M.; Song, B.; Zhao, M. Controlling
Cell Behavior Electrically: Current Views and Future Potential.
Physiol. Rev. 2005, 85 (3), 943–978. https://doi.org/10.1152/
PHYSREV.00020.2004.
9. Langman, L.; Burr, H. S. Electrometric Studies in Women With
Malignancy of Cervix Uteri. Science (80-. ). 1947, 105 (2721),
209–210. https://doi.org/10.1126/SCIENCE.105.2721.209.B.
10. Nuccitelli, R.; Nuccitelli, P.; Li, C.; Narsing, S.; Pariser, D. M.; Lui,
K. The Electric Field near Human Skin Wounds Declines with Age
and Provides a Noninvasive Indicator of Wound Healing. Wound
Repair Regen. 2011, 19 (5), 645–655. https://doi.org/10.1111/
J.1524-475X.2011.00723.X
11. Phillips, M. B.; Nigam, A.; Johnson, J. W. Interplay between Gating
and Block of Ligand-Gated Ion Channels. Brain Sci. 2020, 10 (12),
1–22. https://doi.org/10.3390/BRAINSCI10120928.
12. Luo, R.; Dai, J.; Zhang, J.; Li, Z. Accelerated Skin Wound Healing
by Electrical Stimulation. Adv. Healthc. Mater. 2021, 10 (16).
https://doi.org/10.1002/ADHM.202100557.
13. Levin, M. Bioelectric Signaling: Reprogrammable Circuits
Underlying Embryogenesis, Regeneration, and Cancer. Cell 2021,
184 (8), 1971–1989. https://doi.org/10.1016/J.CELL.2021.02.034.
14. Fraser, S. P.; Ozerlat-Gunduz, I.; Brackenbury, W. J.; Fitzgerald,
E. M.; Campbell, T. M.; Coombes, R. C.; Djamgoz, M. B. A.
Regulation of Voltage-Gated Sodium Channel Expression in
Cancer: Hormones, Growth Factors and Auto-Regulation. Philos.
Trans. R. Soc. Lond. B. Biol. Sci. 2014, 369 (1638). https://doi.
org/10.1098/RSTB.2013.0105.
15. Yildirim, S.; Altun, S.; Gumushan, H.; Patel, A.; Djamgoz, M. B. A.
Voltage-Gated Sodium Channel Activity Promotes Prostate Cancer
Metastasis in Vivo. Cancer Lett. 2012, 323 (1), 58–61. https://doi.
org/10.1016/J.CANLET.2012.03.036.
16. Djamgoz, M. B. A. Treatment of Cancer/Inhibition of Metastasis.
US20180346431A1, June 7, 2018.
17. Paré, J.-F.; Martyniuk, C. J.; Levin, M. Bioelectric Regulation
of Innate Immune System Function in Regenerating and Intact
Xenopus Laevis. npj Regen. Med. 2017 21 2017, 2 (1), 1–15.
https://doi.org/10.1038/s41536-017-0019-y.
Publicado
2023-05-08
Como Citar
Ribeiro, S. M., Teixeira, C. C., & Silva, O. N. (2023). A Bioeletricidade Pode Revolucionar a Medicina. Revista Processos Químicos, 16(32), 64-67. https://doi.org/10.19142/rpq.v18i32.669
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